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Advantage Multi (Advocate) for Dogs

Starting at Only: $36.56
Information
Advantage Multi (Advocate) Flea, Worm, and Heartworm Control
Advantage Multi (Advocate) Flea, Worm, and Heartworm Control for Dogs is a convenient monthly topical solution designed to provide broad-spectrum parasite protection in one simple application. This easy-to-use spot-on treatment helps protect dogs from fleas, heartworm disease, and common intestinal worms, including roundworms, hookworms, and whipworms.
The fast-acting formula starts killing fleas on contact—without requiring them to bite—and supports ongoing protection for a full month. Suitable for dogs and puppies from 7 weeks of age and older, it offers a reliable and stress-free way to manage both internal and external parasites.
Coverage
Advantage Multi (Advocate) helps protect against:
- Fleas (adult fleas and flea infestations)
- Heartworm disease
- Roundworms
- Hookworms
- Whipworms
- Mites (including ear mites and mange)
- Lice
- Aids in the prevention of flea tapeworm
How it Works
Advantage Multi contains imidacloprid and moxidectin, which work together to provide comprehensive parasite protection.
- Imidacloprid acts on the nervous system of fleas, killing them on contact and helping break the flea life cycle.
- Moxidectin is absorbed through the skin into the bloodstream, where it helps prevent heartworm disease and treats internal parasites.
This dual-action formula works from the outside in, delivering consistent protection against a wide range of parasites with monthly use.
Directions
- Weigh your dog to select the correct dose.
- Remove the applicator tube and open it as directed.
- Part the hair until the skin is clearly visible.
- Apply directly to the skin:
- Under 55 lbs: apply at one spot between the shoulder blades
- Over 55 lbs: divide dose across multiple points along the back
- Avoid contact with eyes and mouth.
- Allow the application site to dry completely.
- Apply once monthly for continuous protection.
Dosage:
| Dog Size | Dog Weight (lbs) | Pack Color | Tube Volume (ml) | Active Ingredients (g/L) | Doses |
| Small Dogs | 3.0 – 9.0 | Green | 0.4 | 100 Imidacloprid / 25 Moxidectin | One |
| Medium Dogs | 9.1 – 20.0 | Aqua | 1.0 | 100 Imidacloprid / 25 Moxidectin | One |
| Large Dogs | 20.1 – 55.0 | Red | 2.5 | 100 Imidacloprid / 25 Moxidectin | One |
| Extra Large Dogs | 55.1 – 88.0 | Blue | 4.0 | 100 Imidacloprid / 25 Moxidectin | One |
| Dogs over 88 lbs should be treated using an appropriate combination of tubes. | |||||
Key Benefits
- Broad-spectrum parasite protection in one monthly dose
- Kills fleas on contact—no biting required
- Helps stop reinfesting fleas from biting within minutes
- Supports prevention of heartworm disease
- Helps control intestinal worms and external parasites
- Easy-to-apply topical solution
- Provides continuous protection between doses
- Suitable for puppies and adult dogs
- Available in multiple weight-specific packs
Safety
- For topical use in dogs only.
- Suitable for dogs and puppies from 7 weeks of age.
- Do not use in puppies under 7 weeks.
- Safety not established for pregnant or lactating dogs—consult your veterinarian.
- Use with caution in sick or debilitated dogs.
- Avoid contact with eyes, mouth, and application site until dry.
- Wash hands after use.
- Keep out of reach of children and pets.
- Store below 25°C in a dry place.
More Info
Ingredients
Imidacloprid and Moxidectin
Suitability
- Dogs and puppies from 7 weeks of age and older
- Dogs weighing 3 lbs or more
- Dogs requiring flea and heartworm prevention
- Dogs at risk of intestinal worms, mites, or lice
Available Options
- 3-dose pack
- 6-dose pack
- 12-dose pack
Available in color-coded packs based on weight ranges:
- Small dogs (3.0–9.0 lbs) – Green
- Medium dogs (9.1–20.0 lbs) – Aqua
- Large dogs (20.1–55.0 lbs) – Red
- Extra large dogs (55.1–88.0 lbs) – Blue
Helpful Tips
- Treat all pets in the household to help manage flea infestations.
- Apply on the same date each month for consistent protection.
- Avoid bathing immediately after application.
- Regular use helps reduce environmental flea populations.
- Consult your veterinarian for a complete parasite control plan.
Reviews
Perfect heartworm preventive
A perfect heartworm preventive for my pet.
Amazing
Amazing product. Works well for my buddy.
Proper flea destroyer
Advantage Multi is a proper flea destroyer. Amazing to say the least.

