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Frontline Plus vs. Capstar – Which One is Better For Your Cats?

  Aug 28, 2025

Frontline Plus vs. Capstar – Which One is Better For Your Cats?

Cats of all breeds and ages are susceptible to flea and tick infestations. The parasites tend to attack our feline babies and cause various harmful infections and diseases. Therefore, it is crucial for cat parents to use effective parasite control treatments to keep the pesky parasites at bay.

In this blog, we will walk you through two popular flea and tick treatments for cats, Frontline Plus and Capstar. We will also provide a detailed comparison between the two remedies to help you choose the one that suits your kitty. Read on to find out more.

Frontline Plus vs. Capstar - A Quick Glance

Frontline Plus for Cats

Frontline Plus for Cats comes in the form of a topical treatment indicated to kill fleas, flea eggs and flea larvae. It also prevents all flea life stages from developing, thus stopping existing infestations and preventing new ones.

The treatment also kills fleas, which may cause flea allergy dermatitis. It further kills all life stages of ticks, including brown dog ticks, American dog ticks, lone star ticks and deer ticks. Additionally, the treatment kills ticks that may transmit Lyme disease and other tick-borne diseases. Frontline Plus also rapidly eliminates chewing lice infestations. It is formulated for monthly administration and is suitable for cats and kittens from 8 weeks of age, weighing at least 1.5 lbs.

Capstar for Cats

Capstar for Cats comes in the form of oral tablets indicated to kill adult fleas, including the ones that cause Flea Allergy Dermatitis. It is designed for cats and kittens from 4 weeks of age, weighing at least 2 lbs.

Similarities & Differences

Here are the key similarities and differences between Frontline Plus & Capstar.

Similarities:

  • Both Frontline Plus and Capstar are indicated to kill adult fleas and the ones that cause Flea Allergy Dermatitis.
  • Both treatments can be safely used in pregnant and lactating cats.

Differences:

  • While Frontline Plus is a topical treatment, Capstar comes in the form of oral tablets.
  • Frontline Plus is formulated to act upon a range of parasites, including fleas, ticks and chewing lice. However, Capstar is only effective against fleas.
  • Frontline Plus should be administered monthly. Capstar can be administered up to once per day in case of re-infestation.
  • Frontline Plus is composed of fipronil and (S)-methoprene as its active ingredients. Capster, on the other hand, features nitenpyram.
  • Frontline Plus is approved to be used on breeding, pregnant and lactating cats. Capstar can be safely used only in pregnant and lactating cats.
  • While Frontline Plus is designed for felines from 8 weeks of age, weighing at least 1.5 lbs, Capstar can be used in cats and kittens 4 weeks of age, weighing at least 2 lbs.

Comparative Analysis:

Let’s take a look at a detailed comparison of the key features of Frontline Plus and Capstar.

Frontline Plus vs. Capstar

Frequently Asked Questions

  • Can Frontline Plus and Capstar be used together?

While Frontline Plus provides long-term protection from a range of parasites, Capstar rapidly kills fleas. However, always consult a vet before combining the treatments.

  • Are Frontline Plus and Capstar waterproof?

Frontline Plus is a waterproof formula. Capstar, on the other hand, is an oral treatment.

  • From where can I purchase Frontline Plus and Capstar?

Both Frontline Plus and Capstar can be procured from OurPetWarehouse at the best prices. Check out our online store today!

Wrapping Up

Both Frontline Plus and Capstar are vet-recommended parasite protection for cats. However, they differ when it comes to parasite coverage, mode of application, compositions, as well as age and weight criteria.

If you want protection against adult fleas, you can use either of the treatments. However, if you want to protect your feline against fleas, chewing lice and tick species like brown dog ticks, American dog ticks, lone star ticks and deer ticks, you should go for Frontline Plus. Make sure that your pal meets the minimum age and weight requirements specified on the product labels of the treatments.

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